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Bioactive Affinity

Bioactive Affinity Ingredients | Support Immunity in 3 different ways

Bioactive affinity ingredients, may support immunity in 3 different ways (Block | Modulate | Build)

Block Gut Barrier

A healthy gut barrier helps to block pathogens from entering the body1.
MOS* contributes to a healthy gut barrier2.

Modulate Gut Microbiota

Immunity is crucial for the defense against potential pathogens, meanwhile, beneficial bacteria in gut microbiota plays an important role in immune functioning.
2 types of HMO and MOS* help modulate the gut microbiota closer to breastfed babies3,4. The abundance of beneficial bacteria helps support gastrointestinal health5.

Build Immune Function

An optimal immune system helps protects babies from disease caused by pathogens.
The bioactive antibody (slgA#) plays a key role in maintaining gastrointestinal immune function6.
Study has shown that the levels of slgA#, a type of bioactive antibodies, was found double in fecal samples of babies fed a formula containing MOS2.


Understand more about Bioactive ingredients...

Immunity helps to fight against pathogens and reduces the risk of infection, which is one of the most important parts for baby’s health.
Clinically proven, bioactive affinity ingredients such as 2 types of HMO & MOS*, support immunity in 3 different ways^:
  1. Block | Gut Barrier2
  2. Modulate | Gut Microbiota3,4
  3. Build | Immune Function2

Reduced reporting of lower respiratory tract infection?

Clinically proven, babies receiving formula with 2 types of HMO* were found to have reduced reporting of: 7^*
  • Use of antibiotics
  • Lower respiratory tract infection
  • Bronchitis

Reduced reporting of use of antipyretics?

Clinically proven, babies receiving formula with 2 types of HMO* were found to have reduced reporting of : 7^*
  • Use of antipyretics

Lower counts of pathogens that can cause diarrhea?

Clinically proven, babies receiving formula with MOS :3^*
  • Had lower counts of pathogens that can cause diarrhea
  • Had higher relative abundance of beneficial bacteria including Bifidobacteria and Lactobacilli

^ Compared with control group

* 2 types of HMO refers to 2’-Fucosyllactose (2’-FL) and Lacto-N-neotetraose (LNnT); MOS refers to Milk oligosaccharides

# sIgA refers to secretory immunoglobulin A in fecal samples


  1. Anderson RC et al.. Colitis. 2012. DOI: 10.5772/25753.
  2. Estorninos E et al. Abstract presented at the FASEB Science Research Conferences Nutritional Immunology and the Microbiota: Rules of Engagement in Health and Disease. 24-29 June 2018, Virginia, USA.
  3. Estorninos E et al. JPGN. 2019;58(1):999.
  4. Steenhout P et al. FASEBJ. 2016;30(Suppl 1):275-277.
  5. O’Neill I et al. Emerg Top Life Sci (2017) 1 (4): 333–349.
  6. Bakker-Zierikzee AM et al. Pediatr Allergy Immunol. 2006;17:134-140.
  7. Puccios G et al. JPGN. 2017;64(4):624-631.